Nitrofurantoin 100mg MR is the first-choice antibiotic for uncomplicated cystitis in women: usually one capsule twice a day with food for 3 days. Prescription-only.
The information you give us is kept confidential and is reviewed by a UK prescriber: a GMC-registered doctor or a GPhC-registered pharmacist independent prescriber. Our prescribers use these questions to make sure the treatment is appropriate and safe for you.
Before we can issue a treatment, you’ll need to answer a short assessment. This assessment will help us recommend the right treatment for you.
Start AssessmentCystitis is a bladder infection, and it's the most common type of urinary tract infection (UTI). If you've had it before, you'll know the feeling straight away: burning when you pee, and needing to go again five minutes later. Mild cystitis sometimes clears up on its own within a few days. When it doesn't, a short course of antibiotics usually sorts it out quickly. MedsRus offers nitrofurantoin and trimethoprim after a short online consultation, checked by a UK prescriber.
Cystitis means inflammation of the bladder. It's nearly always caused by bacteria from the bowel getting into the urethra (the tube you pee through) and travelling up into the bladder.
Women get it far more often than men because the urethra is much shorter, so bacteria don't have far to go. Is cystitis a UTI? Yes. It's a UTI of the bladder. Our article on cystitis vs UTI explains the difference between the terms.
Some people have only mild symptoms, or none at all. Our article on silent bladder infections covers the signs that are easy to miss.
Things that make it more likely include:
If your symptoms are mild, it's reasonable to wait a couple of days. Many cases clear up on their own. In the meantime:
If symptoms are bothering you, getting worse or still there after 2 days, antibiotics are the usual treatment. A 3-day course works for most women.
| Nitrofurantoin | Trimethoprim | |
|---|---|---|
| Usual course | 100mg modified-release, twice a day for 3 days | 200mg, twice a day for 3 days |
| How to take | With food | With or without food |
| Good to know | Usually the first choice in the UK. It can turn your pee dark yellow or brown, which is harmless. | Bacteria are more often resistant to it, so it's used when the risk of resistance is low. |
| Not suitable if | You have kidney problems | You're in the first 3 months of pregnancy, or you take certain medicines such as methotrexate |
Most people feel better within a day or two of starting treatment. Finish the course, even once you feel better.
Sometimes, yes. Mild cystitis often settles within a few days without antibiotics. If it doesn't, or you start to feel worse, don't wait: an untreated UTI can occasionally spread to the kidneys.
If you're a woman aged 16 to 64 and not pregnant, you can get UTI treatment from many high street pharmacies through the NHS Pharmacy First service, usually on the same day. Ordering from us suits people who would rather not discuss it face to face, or who can't easily get to a pharmacy. Either way, the medicine is the same.
Get an urgent GP appointment or call NHS 111 if:
Back pain and a fever can mean the infection has reached your kidneys. Our article on kidney infection vs UTI symptoms explains the difference.
Call 999 or go to A&E if someone is confused, very drowsy or has difficulty speaking.
If you get cystitis twice in 6 months, or 3 times in a year, see your GP rather than ordering antibiotics again. They may test your urine, look for an underlying cause, and talk to you about preventive treatment. That might be a low-dose antibiotic, or a vaginal oestrogen cream if you've been through the menopause.
What about cranberry juice? There's some evidence that cranberry products may help stop cystitis coming back in some women, but there's no good evidence that they treat an infection you already have. They're also high in sugar, and you shouldn't take them if you're on warfarin.
Our online service is for women aged 18 to 64 who aren't pregnant.
Cystitis is an infection of the bladder, usually caused by bacteria. It's the most common type of UTI, especially in women.
For mild symptoms, painkillers, plenty of water and rest often do the job within a few days. If you need antibiotics, most women feel better within 1 to 2 days of starting them.
Mild cystitis often clears within 3 days. With antibiotics, symptoms usually ease within a day or two.
Yes, but it's less common, and it needs a GP's assessment. Men usually need a longer course of antibiotics, and the GP may want to rule out a prostate problem.
It may help prevent cystitis coming back for some women, but it won't treat an infection that's already started.
Alcohol doesn't stop nitrofurantoin or trimethoprim working, but it can irritate your bladder, so it's best avoided until you feel better.
Nitrofurantoin can turn urine dark yellow or brown. It's harmless and goes back to normal when you finish the course.
Yes, if you're a woman aged 18 to 64 with typical cystitis symptoms and you're not pregnant. A UK prescriber reviews our online consultation, and NHS Pharmacy First at a local pharmacy is another option. Men, pregnant women and anyone with a fever or back pain should see a GP or call 111.
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