Foundayo (Orforglipron) Weight Loss Tablets

Foundayo is a once-daily weight-loss tablet containing orforglipron, a GLP-1 receptor agonist developed by Eli Lilly. Unlike injectable weight-loss treatments, Foundayo is taken as a tablet and can be taken with or without food, making it a convenient option for people who prefer an oral treatment.

Why choose Foundayo?

Foundayo offers a convenient alternative to injectable weight-loss treatments.

• Once-daily tablet – no injections required
• Take with or without food
• No fasting routine required
• Can be taken at any time of day
• Helps reduce hunger and cravings
• Helps you feel fuller for longer
• Available in six strengths for gradual dose increases

How does Foundayo work?

Foundayo contains orforglipron, a small-molecule GLP-1 receptor agonist.

GLP-1 is a hormone naturally produced by the body that helps regulate appetite, digestion and blood glucose levels. Foundayo activates GLP-1 receptors, helping to reduce hunger and cravings while increasing feelings of fullness.

It can also slow the movement of food through the stomach and influence blood glucose regulation.

Everyone responds differently to treatment. Some people notice changes in their appetite relatively early, while for others the effects develop gradually as treatment progresses.

For the best results, Foundayo should be used alongside a healthy, balanced diet and increased physical activity.

Who is Foundayo suitable for?

In the UK, Foundayo is authorised for weight management and weight maintenance in adults who have:

• A BMI of 30 or above, or
• A BMI between 27 and 30 with at least one weight-related health condition.

Treatment should be combined with a reduced-calorie diet and increased physical activity.

Meeting these criteria does not automatically mean Foundayo is suitable for you. A qualified prescriber will review your medical history, BMI, current medicines and other relevant information before deciding whether treatment is appropriate.

How effective is Foundayo?

Foundayo has been studied in large clinical trials involving adults with overweight or obesity.

In the ATTAIN-1 clinical trial, more than 3,000 adults were treated for 72 weeks. The study found significantly greater weight loss with orforglipron compared with placebo.

At the highest dose, people who remained on treatment for the full 72 weeks achieved an average weight loss of approximately 12.4% of their starting body weight.

Individual results will vary. Your results can depend on factors such as your starting weight, dose, diet, activity levels and how your body responds to treatment.

Foundayo vs Wegovy and Mounjaro

Foundayo, Wegovy and Mounjaro are prescription medicines used for weight management, but they contain different active ingredients and work in slightly different ways.

	Foundayo	Wegovy	Mounjaro
Active ingredient	Orforglipron	Semaglutide	Tirzepatide
Type of treatment	GLP-1 receptor agonist	GLP-1 receptor agonist	GIP/GLP-1 receptor agonist
How often	Once daily	Once weekly	Once weekly
Administration	Tablet	Injection	Injection
Food restrictions	With or without food	No specific fasting requirement	No specific fasting requirement

The main difference with Foundayo is that it is taken as a daily tablet rather than an injection. This may appeal to people who prefer an oral treatment.

Your prescriber will assess your individual circumstances before deciding which treatment may be appropriate for you.

Foundayo dosage

Foundayo is available in six strengths:

• 0.8 mg
• 2.5 mg
• 5.5 mg
• 9 mg
• 14.5 mg
• 17.2 mg

Treatment starts at 0.8 mg once daily. The dose is gradually increased where appropriate to give your body time to adjust and help manage potential side effects.

Foundayo dose schedule

Stage	Dose
Starting dose	0.8 mg
Step 2	2.5 mg
Step 3	5.5 mg
Step 4	9 mg
Step 5	14.5 mg
Maximum dose	17.2 mg

Each dose is normally taken for at least 30 days before moving to the next strength, where appropriate.

You do not necessarily need to reach the maximum dose. Your prescriber will decide whether your dose should be increased based on your response to treatment and how well you tolerate it.

How do I take Foundayo?

Take one tablet once a day.

Foundayo can be taken:

• At any time of day
• With or without food

There is no requirement to fast before or after taking your tablet.

Swallow the tablet whole. Do not crush, chew or break it, and do not take more than one tablet in a day.

If you forget a dose, take it when you remember. Do not take more than one dose on the same day. If you have missed several doses and are unsure when to restart, contact your clinical team.

Foundayo side effects

Like other medicines that act on the GLP-1 pathway, Foundayo can cause side effects. These are most commonly related to the digestive system and may be more noticeable when starting treatment or increasing your dose.

Common side effects can include:

• Nausea
• Diarrhoea
• Constipation
• Vomiting
• Stomach or abdominal discomfort
• Indigestion
• Bloating
• Belching

Most gastrointestinal side effects are mild to moderate and may improve as your body adjusts to treatment.

If you experience severe, persistent or concerning symptoms, contact your prescriber or healthcare professional.

Important safety information

Foundayo is not suitable for everyone.

Tell your prescriber if you have, or have previously had:

• Pancreatitis
• Severe gastrointestinal problems or delayed stomach emptying
• Kidney or liver problems
• Gallbladder problems
• Diabetes or diabetes-related eye problems
• Allergies to medicines
• An operation or procedure requiring anaesthesia or sedation

You should also tell your prescriber about all medicines and supplements you currently take. Foundayo may affect the absorption or processing of some medicines, while some medicines may affect orforglipron levels.

Foundayo should not be taken if you have had a serious allergic reaction to orforglipron or any of its ingredients.

Always read the Patient Information Leaflet supplied with your medicine and follow your prescriber's instructions.

How to Order Foundayo from MedsRUs

Getting started with Foundayo through MedsRUs is simple and can be completed online.

1. Start your online consultation

Choose Foundayo and complete our confidential online medical questionnaire. You'll be asked about your BMI, medical history, current medicines and weight-management goals.

2. Our clinical team reviews your consultation

A qualified prescriber will carefully review the information you provide and assess whether Foundayo is suitable for you.

A prescription is not guaranteed. Treatment will only be prescribed if our prescriber considers it appropriate and safe.

3. Place your order

If Foundayo is prescribed, you can complete your order securely through MedsRUs.

4. Receive your treatment

Once your prescription has been approved and dispensed, your Foundayo will be delivered directly to you in discreet packaging.

Start Your Foundayo Journey with MedsRUs

Foundayo offers a convenient tablet-based option for people looking to manage their weight without injections.

At MedsRUs, you can complete your consultation from the comfort of your own home. Your information is reviewed by a qualified prescriber before any treatment is supplied.

If Foundayo is considered suitable for you, your prescription can be dispensed and delivered directly to your chosen address.

Ready to get started?

Start your Foundayo consultation today.