Acetazolamide tablets help prevent the headache, nausea and tiredness of altitude sickness on trips above about 2,500 metres when a slow ascent isn't possible. It's a prescription medicine used off-label for this purpose, and a UK prescriber reviews your consultation before it's supplied.
The information you give us is kept confidential and is reviewed by a UK prescriber: a GMC-registered doctor or a GPhC-registered pharmacist independent prescriber. Our prescribers use these questions to make sure the treatment is appropriate and safe for you.
Before we can issue a treatment, you’ll need to answer a short assessment. This assessment will help us recommend the right treatment for you.
Start AssessmentAltitude sickness can affect anyone who travels to high places too quickly, usually above 2,500 metres. It's common on treks to Everest Base Camp and Kilimanjaro, and on trips to high cities such as Cusco or La Paz. The best protection is a slow ascent, and for some trips a prescriber may also recommend acetazolamide tablets to help your body adjust. MedsRus can prescribe acetazolamide after a short online consultation with a UK prescriber, and send it by tracked delivery before you travel.
Symptoms usually start 6 to 24 hours after you reach altitude. Mild altitude sickness, also called acute mountain sickness, can feel like a bad hangover:
Serious altitude sickness needs emergency descent. There are two rarer, life-threatening forms. Fluid on the lungs (high altitude pulmonary oedema, or HAPE) causes breathlessness at rest, a cough and sometimes pink, frothy phlegm. Fluid on the brain (high altitude cerebral oedema, or HACE) causes confusion, clumsiness, drowsiness or a severe headache that doesn't ease. If anyone in your group develops these, go down straight away and get medical help.
Being fit doesn't protect you, and having been fine on one trip doesn't guarantee you'll be fine on the next.
Acetazolamide helps your body adjust to lower oxygen levels more quickly. It's used to help prevent altitude sickness on trips where a slow ascent isn't possible, such as flying straight into a high city, or on routes that climb quickly, like most routes up Kilimanjaro.
It isn't a substitute for a sensible ascent, and it won't stop serious altitude sickness if you keep climbing with symptoms.
Acetazolamide is licensed in the UK for other conditions, such as glaucoma, but not for altitude sickness. Prescribing it to prevent altitude sickness is well established and in line with UK travel health guidance, but it counts as "off-label" use. Our prescriber will explain what this means during your consultation before deciding whether it's right for you.
Your prescriber will confirm the dose for your trip. It's usually started 1 to 2 days before you begin your ascent and continued until you've spent 2 to 3 days at your highest altitude, or until you start coming down. If you can, try a dose at home before you travel so you know how it affects you.
These are usually mild. Stop taking it and get medical advice if you develop a rash.
It isn't suitable if you're allergic to sulfonamide ("sulfa") medicines, are pregnant or breastfeeding, or have serious kidney or liver problems. Tell the prescriber about any other medicines you take, especially high-dose aspirin.
Heading somewhere with a malaria risk? See our malaria tablets page. For long-haul flights, our jet lag treatment page explains how to adjust to a new time zone, and our travel health checklist helps you plan before you go.
It's most common above 2,500 metres, though some people notice symptoms lower down, especially after a fast ascent.
Many trekkers take acetazolamide for Kilimanjaro because most routes climb quickly. Our prescriber will advise based on your route and how many days it takes.
It's mainly used to prevent altitude sickness. If you get symptoms, stop climbing and rest, and go down if they don't improve. Don't rely on tablets to keep going.
No. It lowers the risk, but a slow ascent is still essential.
Mild altitude sickness usually settles with rest. HAPE and HACE are life-threatening and need immediate descent and medical help.
Yes, and they may not be able to describe their symptoms. Our service is for adults, so ask a travel clinic about children.
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